The arbitrary response when a male accomplice talks about, or even merely refers to, your sister. Often, the one that mentioned her gets cut off mid-sentence, the other not even caring about the remaining sentence.
"Hey dude, isn't that your sis--"
"No chance, bro."
"Huh?"

"Man, your dad just called your sister had a car cr--"
"No chance, bro."
"Hell is wrong with you, boy?!"
by Chiggaman January 7, 2009
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Better know as Two Scoops of Chance

Chance Bro was created in Chicago Illinois.

is pretty much means no
i need a better definition
Mgo: Think we should go help N#gga Bags with the luggage?
Hrag:Chance Bro( and we walk away)

Camper #1:Can I my phone tonight?
Unger Mgo:Chanceee(British accent)
by N#gga Mgo October 23, 2009
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