Top definition
The arbitrary response when a male accomplice talks about, or even merely refers to, your sister. Often, the one that mentioned her gets cut off mid-sentence, the other not even caring about the remaining sentence.
"Hey dude, isn't that your sis--"
"No chance, bro."

"Man, your dad just called your sister had a car cr--"
"No chance, bro."
"Hell is wrong with you, boy?!"
by Chiggaman January 07, 2009
Get the mug
Get a No Chance, Bro mug for your cat Manley.