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"Nature's callin" or "nature calls" is usually how nature's call is said in a sentence.

Guy #1: Dude, where you going so fast?

Guy #2: Nature calls!
by chocolate box July 22, 2006
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May 16 Word of the Day
Abbreviation for:

I DON’T GIVE A FUCK WHAT THE CDC SAYS YOU BE WEARING YOUR MASK
Karen: The CDC says we can stop wearing maβ€”
Frank: IDGAFWTCDCSYBWYMFM !!!!!!
via giphy
by Callmemaybe69 May 14, 2021
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2
noun A term used to define, in a G-Rated dialect, the urge to take a massive dump.
1. Jimmy: You don't look so good. What's the rush?
Timmy: I have to answer nature's call!

2. Kimmy: Hey, what's up?
Bimmy: One moment, nature calls.
by cool guy with cool shoes June 06, 2015
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