The act of placing half of a straw up a man's urethra and the other half up another man's urethra. The pair can then proceed with fluid exchanges in the form of semen or urine.
Mike had just finished his fruity smoothie with Raph. The straw was tempting so they performed a Mississippi pipeline.
by ForMikeD June 17, 2011
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The homosexual act of placing half of a straw up a man's urethra and the other half up another man's urethra.

The men will then proceed in exchanging bodily fluids such as urine and semen.

Creative men can play a form of tug of war to determine who possesses the more powerful pee stream.
Mike was horny, Raph was in the room, and the straw from the fruity smoothie they had just shared was too tempting. They proceeded by creating a mississippi pipeline, filling each other's bladders.
by this is for mike June 8, 2011
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The act of having several (5 or more) black men run a train on a person.
Nick: Did you hear what happened to Courtney last night?
Taj: Yeah, she got Mississippi Pipelined.
by WAKEUPWAKEUPWAKEUP May 2, 2023
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