To be annoying to someone else, or to get someone else mad. Also used as the ultimate ponage word (even more affective then pwnzorafied1337h4xatroned).

The word, joe mama(x5), mainly conveys that you are not listening to someone else's negative, or worthless, comments.
Random man 1: Dude, sup homie corndog?
Random man 2: uhh.... nuttin' much, actually!
Random man 1: You know what? i had the most boring day in my life! I got pwoned by someone saying that im a pwoink! i--(keeps yammering, or talking trash....)
Random man 2 (in his head): *Joe mama joe mama joe mama joe mama joe mama joe mama..*
by Cauterize May 16, 2007
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A really long, rippling fart, which sounds like the sound effect on Scooby Doo when they run on the spot madly after seeing a ghost.
And next on Classical Musician of the Year, John Cage will play Chorus like Mama Joe's Bongos, on the rusty sherriff's badge.
by Oni-91 October 26, 2007
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A clever name used to insult another individual's mother. It is a play on words that refers to the saying, "Yo mama!"
Person 1: "Where's Joe?"
Victim 1: "Joe? ... Joe who?"
Person 1: "JOE MAMA!"
Victim 1: *Proceeds to feel insulted*
by B-Man February 02, 2004
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An insult that when asking "who's joe*" you become a disappointment to society and you burn in bruh moment hell
Guy 1: I see Joe
Guy 2: who's joe
Guy 1: JOE MAMA
*instantly becomes disowned and lives rest of life in shame
by Joe Mama 69420 October 23, 2019
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If you are reading this chances are you asked who joe is. By doing this you have made your brain ten times smaller and you are no longer a functioning member of society. You have disappointed the gods and you will live the rest of your life in a bruh moment. Side effects of asking who joe is might include death.
Friend#1: Do you know who joe is?
Friend#2:who’s joe???
Friend#1:you fool you moron you absolute buffoon you have fallen right into my trap!!! You want to know who joe is? Why he is JOE MAMA!!!
Friend#2: NANI!! MY BRAIN IT IS SHRINKING *dies*
Friend#1: ah ha! Taste defeat you fool!
by Microwave man September 17, 2019
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Paul: “hey have you seen Joe?”
Bill: “no, who’s Joe?”
*NUCLEAR SIRENS*
Paul: “Joe Mama”
*Big ass fucking explosion
by Lord_ Cocken_of_Dongshire December 17, 2019
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