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Loc'd is another way of saying "gangstered up." It refers to being in the mindset of doin' dirt or gang activity such as shooting up a place (usually refers to violent crime) or it could possibly mean that you are just in the mood to do some gangbanging.
"I uncocked my shit, I was heartbroke, but I was still Loc'd"
-Snoop Dogg

"All of a sudden niggaz start trippin, flippin', the record start skippin', wildin', fools start loc'n up gats crack the room start smokin' up"
-Ice T

"I seen some dope boys on my corna so I got fuckin' Loc'd up and grabbed the four-fifth cocked it and doused those little niggaz, now they ass leakin'."
by ErbGotti March 03, 2009
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Stands for Lying Obsessive Compulsive Disorder. Not a real disease of course, but the difiniton is:
A person who tells many lies and they think they are getting away with it.
When people start to ask questions, they make up more and more lies to cover up, then there is a whole big web of lies. A person with LOCD doesn't know they have LOCD.
Kate: I thought you said you saw Lucy at the shops on saturday, but she said she went to the movies with her boyfriend.

Emily: Yeah when i asked her what movie she saw she said that she "forgot"

Kate: haha, i think she has developed LOCD
by sandshoe May 01, 2009
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