League of Legends players' who are normal quiet players. All of a sudden, they say toxic remarks such as: "kill yourself" "i hope you jump off a bridge" "cancer" "autism" or all of the above at the same time. These are players who feel insecure about themselves. They're the type of players to act innocent if you call them out on their toxicity in post-game chat, If they act innocent after they flame someone mid-game then they have a severe case of League Syndrome. They're the type of players to justify their negative attitude.

If you want a master manipulator then you need someone who has League Syndrome because those fuckers take shit out of their ass and smear it on their chat box.
Player 1: "Can you stop being toxic?"
Player 2: "Shut the fuck up faggot piece of shit you cancerous toxic fuck, you're the toxic one."
Player 3: "Wow, HOLY LEAGUE SYNDROME"
by LeagueMaster3000 October 19, 2016
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The 'Rocket League Syndrome' affects entertaining Youtubers during their recordings. It is a mental irritation that comes with its physical symptom of giving the affected person an itchy nose.

Several famous Youtubers are already infected with the Rocket League Syndrome. It is said that patient zero is either JonSandman or Woofless, both whom are famous Youtubers that play Rocket League frequently.

There is still no known cure to the Rocket League Syndrome.
I'm going to play defensive, the Rocket League syndrome is messing with me again. (Which essentially means that the person is staying as a goalkeeper so that he/she can scratch his nose)
by JNse April 13, 2017
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A rare contagious disease that causes multiple personality disorder causing those infected to act in strange ways. This disease is brought on by spending too much time in flops fantasy football or interacting with those who have been diagnosed with the disease
Yo what happened to jack he keeps telling me to kms and is claiming hes the Vice President? Oh you didnt hear he joined flops league and caught Flops league Syndrome.
by flops league knower August 3, 2023
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