A response to "are you sure?" if you have HIV and are sure about something.
Kyle: Are you sure?
Cartman: I'm HIV positive.
by OMGary March 15, 2008
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That cartman says when he is asked if he is sure.
episode 1201
Butters:Are you sure we should be doing this?
Cartman:Butters, i'm not just sure, i'm HIV positive!
Butters: OH well i guess thats true..
by Samanthaa* March 18, 2008
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It's when someone is coming on to you, that does not currently, nor ever will have a shred of a chance.
Guy/Girl: Your so Handsome/Pretty...
Response: Well I'll have you know, that I'm HIV positive, and allergic to latex...
by 69hysteria87 October 10, 2019
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