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A cordial way of saying who gives a fuck, fuck off, or shut the fuck up. This expression is particularly useful in online conversations or when you need to silence someone in their tracks.
Jack: So let me tell you what I did today. I fed my cat, polished my shoes, bought a new hat, but I still didn't get any work done on my damn--

Greg: Greetings from London!

Jack: Sorry about that.
by avery_brooks July 23, 2008
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