basically telling someone "fuck you" without saying those words. telling someone to shove their dick up their asshole and like it. appropriate for almost all emotions, anger, aggravation, sadness, and hate.
you're an asshole. go fuck yourself
by tired of assholes March 13, 2010
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Another way of saying "your a asshole, go away"

"I Don't Like Your New Hair Color"
"No One Cares Bitch, Go Fuck Yourself"
"I Don't Like Your New Hair Color"
"No One Cares Bitch, Go Fuck Yourself"
by ScandalousC October 31, 2014
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The unofficial slogan of New York City. It is used to end or pre-empt a conversation.
"Does the G line stop at Rockefeller Center?"
"Do I look like a godamn tourist kiosk? Go fuck yourself."
by Seventh Planet August 7, 2015
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In New England, it's used amongst friends to tell them, "we're cool" "it's all good" "don't fucking worry about it
Sully: dude, here's a fivah, for beer.

Fitzy: go fuck yourself

Sully: see ya tomorrow
by Sully435345 May 28, 2011
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Friend : HAHA You So Suck at this game

Me: Go Fuck Yourself
by GamerDude887 February 25, 2013
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If you need to look this up, you should try this sometime.
Tony: Go fuck yourself Steve, not my girlfriend!
Steve: What does go fuck yourself mean?
Tony: Do it douchebag.
by That_guy_over_there_42 July 11, 2014
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