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1) A sarcastic remark to a statement that is obviously not going to happen, or something that you do not want.

2) Kind of like an insult; a comeback to say to some one.
1) Ron: So I heard you and Eugene are going to start dating?
Jen: Fuck you in the mouth, no we're not.

2) Jack: Your just a bitch
Lisa: Fuck you in the mouth
by babigurl671 November 27, 2007
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