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Butthole Cancer 

Butthole Cancer is another way of referring to anal cancer. Anal cancer is a type of cancer that occurs in the anal canal and the anus. It is a rare disease among the general population, but is very common among gay men. Along with that, infections like HIV and Syphilis are also very common among gay men.

Gay men who don’t have HIV are over 20 times more likely to get anal cancer than the general population. Gay men who DO have HIV are about 100 times more likely to get anal cancer. Rates of anal cancer among gay men have been increasing every year.

This is because gay sex often causes anal fissures or tears. The anus is supposed to remove waste from the body, and having gay sex will eventually cause tears and cuts to the anus. These tears can get infected.
If you're a gay man, then your chances of getting infections and diseases like HIV, AIDS, Syphilis, and anal cancer (or butthole cancer) are quite high.
Butthole Cancer by Medical School October 18, 2019
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butthole cancer 

A less serious name for anal and/or colon cancer
Dr. Gupta: You have butthole cancer.

Mr. Larrity: What are you talking about?

Dr. Gupta: It affects 99% of CEOs and 100% of politicians at some point in their lives. We will have to remove your butthole before it spreads.
butthole cancer by ThomasGRogan November 26, 2009

butthole cancer 

a more humorous form of colon cancer
johhny: dude, my gerbil just died. doc says its from colon cancer.
Johnny: wtf? how did he get butthole cancer?
butthole cancer by tallywacker June 10, 2008

Cancer in butthole

In a nutshell its League of Legends, You just open a game and everyone starts fucking you in your butthole.
well known from south park
rednecks get angrry that future folk took there jobs so they yell
They took ouare jerbs!
Them future folk took ouare jerbs!
jerb by Jimberley Kim April 7, 2005
Word of the Day on May 22, 2026
An Irish phrase meaning shit, derived from ass
(Not to be confused with the literal description of one's buttocks)
"Did you hear the song Aylek$ dropped?"
"Hardly. Her music is absolute cheeks."

"My boyfriend say LaFlame is cheeks."
"Tell your boyfriend I said it's his mixtape that's cheeks."
Cheeks by thecartisan April 26, 2020
Word of the Day on May 21, 2026

sans sheriff 

Lawless use of fonts or typography, with no regard to aesthetics or legibility
I'm putting this CV straight in the bin. Written totally sans sheriff.
sans sheriff by Jamarley July 3, 2019
Word of the Day on May 20, 2026