similar to 4sho, except when you say 4sho you are just saying "for sure", whereas when you are 5sho you are extremely "for sure". used only on instant messenger.
person #1: "yo you feelin that new T.I. cd?"
person #2: "5sho"
person #1: "damn it was that good foreal?"
person #2: "yeah man cop that shit"
by J-Smoove March 31, 2006
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