Albany, NY. This phrase is used as a name for this city because it is the local area code. In most cases, one will say "the 518" rather than just "518".
"This weekend is gonna be crazy man. We'll be partying up in the 518 cuz we're seein a concert there on Friday."
A Youtuber that likes to speak Italian for his intro and likes to say mate. He also plays with his best friend Benjo and wastes his money on TF2.
C.J.: Ciao everyone! C.J.51801 in the house! and welcome to TF2! I'm here with my friend Ben and he is exited to pla-
Benjo: Shut your fucking mouth you god damn mother fucking bitch damn fuck cock shit!
A YouTube video that plays the Portal Radio loop for 10 hours, After 5 hours, 18 minutes, and 48 seconds, The radio loop is interrupted by a half naked man who states "Time to do some push ups." He proceeds to go through a workout routine while simultaneously ripping ass. I mean actual butt hole destruction, like he makes lawn mower sounds from his ass.
Tom: Time to listen to my favorite video Portal Radio 10 Hours, I hope a man in his underwear doesn't interrupt 5 hours, 18 minutes, and 48 seconds in! Imagine if something happened to Portal Radio 10 hours 5:18:48:14 in!
King of Ass Ripping: J ͖̠̖̘̇̑̀͝o ̖͈̜͉̾̓h̴͉͂̇́n̴̞̲̣͓̕ ̟̐̃̚͜D ̱͌e̶̯̣̭̍̒̋͂ȩ̵̘̥̪̓̐ŕ̶͖͚̱̹͊ ̭̀̍̃͝T ̯̗̫̭͊̅͘r̶͕̾͐̎͠ã̶̝̖c ̧̄t ̰̻̌͑o ͍̂̃͂r̴͖̙͑̌ͅ ̵͕̎̓̈́Ă̵̦̰͐S̴̞̪̚͜ͅM̴̯̯̾̊R̴̦̘̤͐͐͛̀
Tom: GYATT!
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.