A character aside from the main character, irregardless of gender (don't worry, no homo), particularly in an anime that has the most influence in how the plot moves along the series.
Characters that best personify this include: Speedwagon in Jojo's Bizarre Adventure and Kongming in Paripi Koumei.
Speedwagon is best girl
Speedwagon is best girl
by Ayame Ao June 26, 2022
Get the Best girlmug. 
Someone who you thought was your friend but then now you don’t wanna be seen with her and she’s just downright a bitch
by Someonewhohateslife May 8, 2024
Get the A Girl Best Friendmug. by Aubrey__ November 2, 2021
Get the National Girl Best Friend Daymug. A girl best friend will always be there for you no matter what anytime and will make fun of you ALL THE TIME and be mean to you but it’s just because she is comfortable with you because she would never to do that to anyone else but will always stand up for you and is the only one allowed to talk smack about you. She is also the person who will help you with girls and give you advice. A girl best friend will also never lie to you, tell you when you’re wrong, and people will always think you’re more than friend. You go to her for style choices and anything you need help with.
someone: you’re like really close to that girl are y’all a thing?
boy best friend: Nah she’s my girl best friend.
boy best friend: Nah she’s my girl best friend.
by ur bestieee December 28, 2020
Get the Girl Best friendmug. by Lilbittt225 January 18, 2021
Get the National appreciate your girl best friend daymug. You probably searched this up hoping that the definition would be you. This is the definition so you can decide whether this is you or not. The best girl ever is.............YOU! JK! There's no such thing as the best girl ever.
by preppygurl7 January 2, 2025
Get the best girl evermug.