That person, normally a female, who defines everything that warrents your scorn. This term should only be said to the person it describes if you know you will never want anything from her (or him), including, but not limited to, sex, booze, sex with her sister or friend.
girl: can i sing for you?
boy: yea sure
girl: TINKY WINKY DIPSY LAA LAA AND MOTHERFUCKING PO boy: OMG
boy: you’re amazing boy: i love you
girl: IT’S A SOLO
Another word for motherfucker, but instead your so wasted and high that you don't even give a damn fuck no more about how you look or do because white girl over there got you hammered and banged you in the club while your cussing your friends/nightstand the fuck out...
Tony: Sorry man, I was watching tons of porn on your laptop and now it has viruses everywhere
Jack: You ugly ass motherfucka, this is the 2nd time already dammit!