Down syndrome

Lukas ;)

Lukas has Down syndrome

by Urlocalnugget August 15, 2020

Down syndrome

Someone with an extra chromosome

He liking his balls i think he has Down syndrome

by Illegal border hopper April 21, 2022

Down Syndrome

when you have all the chromosones

Yea Nathan have down syndrome

by boudaciousslayqueen420 June 9, 2022

Down syndrome

A retarted ass dog named duke that has 3 missing chromosomes and likes dick up his ass and having cats shoved up his ass

Person 1 : how’s down syndrome

Person 2 : he’s not Down syndrome it’s fucking duke

by Retartedmonkey August 16, 2023

down syndrome

cody zinkus down syndrome

cody zinkus looks like a sped down syndrome

by bubblebath280 December 20, 2023

Down Syndrome

Also known as Trisomy 21. With 23 pairs of chromosomes, a person with Down Syndrome (i.e., a retard) has an extra 21st chromosome, causing several physical and mental defects. Usually easily recognized due to the retarded shape of their face and the clueless, happy expression on their face. These poor brain-dead sacks of sweaty garbage might be able to hold down a job as a greeter at Walmart, but this is about as high up the corporate ladder that these circus freaks typically go.

"Oh my god, did you see that dipshit window-licker trying to parallel park a shopping cart? What a down syndrome, fat fucking gay retard, fucking just dumbass stupid fucking loser. Let's kill him. I'll drown his ass, what a fucking puke piece of shit."

by Jack-the-stripper-ripper May 2, 2025

down syndrome motherfucker

When you are really pissed off at someone who is normal(not retarded in anyway) and has a slightly down syndrome look face, you yell at them "what the fuck are you looking at, you down syndrome motherfucker!! This releases stress and puts a great big smile on your face. Try it today!

No examples needed for down syndrome motherfucker. You can fit it in with just about anything.

by Mr. Fuko March 5, 2011