by Fat men always pro vale. June 11, 2016
Get the Super Duper Sumos mug.To act like or mimic accidentally Muskegon Michigan's own superstar Facebook celebrity Mr.Suboxone aka Kody Winning Allen
What the fuck dude I paid you and now you are gonna pull a total Mr. SUBOXONE like that. Eat shit dick head.
by Murseh8r January 23, 2022
Get the Mr. SUBOXONE mug.by schultza July 20, 2005
Get the sumolians mug.Suboxone is the trade name for a medication that contains buprenorphine and naloxone. A very similar medication, Subutex, contains buprenorphine without naloxone. Both are manufactured and sold by a British company, Reckitt-Benckiser, and are scheduled to lose their patent protection in 2009. Both medications are indicated for treatment of opiate dependence, and both are also used 'off label' to treat chronic pain.
The active substance, buprenorphine, has effects at the mu opiate receptor that are different than effects of pain pills or methadone. Oxycodone, methadone, and hydrocodone are all 'agonists', meaning that the more drug, the more effect at the receptor. Naloxone and Naltrexone are mu 'antagonists'-- they will block the effects of pain pills and have no stimulating effect at the receptor. Buprenorphine is a 'partial agonist'-- in between the two. It will activate the mu receptor and relieve pain up to a certain point, where it has a 'ceiling' to it's effect. Beyond that point, any increases in dose of buprenorphine will have no extra effect. Buprenorphine becomes an 'antagonist' at that point, blocking the receptor so that any other opiate medications will be ineffective.
The result is that treatment with buprenorphine virtually eliminates cravings for opiates in opiate addicts who use it properly. It can be taken once per day, and will also block the effects of any other opiates the addict may take. Because of these effects, buprenorphine is considered a 'remission agent'-- it will induce remission of opiate addiction, but it is NOT a cure. When an addict stops buprenorphine, all of the prior features of his/her addiction will return if the addict does not do something to replace the buprenorphine-- such as become involved in 12 step groups.
While not a cure, there is no truth to the oft-heard comment that buprenorphine is only 'replacing one drug with another'. Opiate addiction consists of the obsession for opiates; the addict's mind is taken over by the singular concern for finding the next dose. Buprenorphine effectively treats addiction by eliminating the obsession far beyond what occurs with taking an opiate agonist.
More and more addictionologists are recognizing that buprenorphine and Suboxone should be considered long term treatments.
The active substance, buprenorphine, has effects at the mu opiate receptor that are different than effects of pain pills or methadone. Oxycodone, methadone, and hydrocodone are all 'agonists', meaning that the more drug, the more effect at the receptor. Naloxone and Naltrexone are mu 'antagonists'-- they will block the effects of pain pills and have no stimulating effect at the receptor. Buprenorphine is a 'partial agonist'-- in between the two. It will activate the mu receptor and relieve pain up to a certain point, where it has a 'ceiling' to it's effect. Beyond that point, any increases in dose of buprenorphine will have no extra effect. Buprenorphine becomes an 'antagonist' at that point, blocking the receptor so that any other opiate medications will be ineffective.
The result is that treatment with buprenorphine virtually eliminates cravings for opiates in opiate addicts who use it properly. It can be taken once per day, and will also block the effects of any other opiates the addict may take. Because of these effects, buprenorphine is considered a 'remission agent'-- it will induce remission of opiate addiction, but it is NOT a cure. When an addict stops buprenorphine, all of the prior features of his/her addiction will return if the addict does not do something to replace the buprenorphine-- such as become involved in 12 step groups.
While not a cure, there is no truth to the oft-heard comment that buprenorphine is only 'replacing one drug with another'. Opiate addiction consists of the obsession for opiates; the addict's mind is taken over by the singular concern for finding the next dose. Buprenorphine effectively treats addiction by eliminating the obsession far beyond what occurs with taking an opiate agonist.
More and more addictionologists are recognizing that buprenorphine and Suboxone should be considered long term treatments.
I am sick and tired of chasing after 'contins, so I'm going to find a doc certified to treat me with Suboxone.
by SuboxDoc December 15, 2008
Get the Suboxone mug.Sumo wrestling involves 2 fat REALLY REALLY fat guys that EAT heaps and heaps of food al the time to get really really fat and try and push eachother over or out of the ring, it is a national Sport and Japan's FAVOURITE sport!!!!!
by Mr.wankk March 2, 2007
Get the sumo wrestling mug.The suboxone can only be properly dosed if you are smack dab in the middle of your withdrawal, so the doctors can see the level of dependence. They say stop taking everything 48-72 hours before your appointment. You should be dosed right there in the office that day. I have had many friends with success but some had relapses too because if you stop your suboxone therapy too soon the craving returns as intense as before the treatment. We all have our struggles and demons. If you're reading this considering suboxone therapy, please know you're not alone. I start in two weeks. I'm scared, but I'm ready.
I am spending way too much money on these pills, but I can't stop by myself. Maybe I'll try suboxone therapy.
by ellam71106 May 12, 2009
Get the Suboxone mug.Hint: Don't go to a sumo wrestling match if you are not a sumo wrestler. Sumo wrestlers are so heavy that they will kill you once they step on you. Beware.
by LOLLERZZZZZZZZZZZ April 21, 2009
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