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hippie speedball 

A joint and an espresso.
I can't do anything in the morning until I've had my hippie speedball.

Stoner speedball 

A milder version of the "kiddie speedball," the Stoner speedball is when users ingest or smoke marijuana (depressant) and drink copious amounts of coffee or energy drink (stimulant). A safe alternative.
Dan: Hey you want try a speedball?

Matt: No thanks brah I'm stoner speedballin'
Stoner speedball by BME222 January 3, 2010

Poor Man's Speedball 

Smoking marijuana and drinking caffeine at the same time.

(Pot and caffeine vs. heroin and cocaine in a real speedball.)
This poor man's speedball is just what I needed to clear this hangover.
Poor Man's Speedball by Chick Henry September 22, 2008

Hipster Speedball 

Drinking espresso, or other coffee shop drinks, while smoking marijuana.
I am going to stop by the Bean Fiend tonight, hang out on the back deck, for a quick Hipster Speedball before I ride my fixie downtown to check out Hadag Nachach. You've probably never heard of them.
Hipster Speedball by ObservingSCAD September 22, 2011

Hillbilly Speedball

When a redneck mixes Oxycontin with five hour energy drinks to get high.
Beauregard:"We got so wasted on Oxys last night."

Ewalt:"Did you get the nods"

Beauregard:"No man we each took a Hillbilly Speedball it kept us up raging all night"

purple skittle hippie speedball

Yuppie Speedball 

An unwise mix of overpriced coffee and prescription sleep aids.
Traveler 1: Why are you taking a Starbucks double espresso with you on the plane? I thought you said you were going to try and sleep off your jet lag?
Traveler 2: Oh that won't be a problem, I'll take an Ambien.
Traveler 1: Is that safe? That's like some kind of Yuppie Speedball.
Traveler 2: Like what killed Jim Belushi?
Traveler 1: No, you mean John Belushi, but yes.