Osu 

osu! is a freeware rhythm game originally for Microsoft Windows. It is written in C# on the .NET Framework. The game has also been ported to Mac OS X, iOS, and Android. Its gameplay is based on commercial titles including Osu! Tatakae! Ouendan, Elite Beat Agents, Taiko no Tatsujin, beatmania IIDX, O2Jam, and DJMax.

Despite the stupidity stupidity of some; it is pronounced Oh-Sue. Not OOS.

A: Have you heard that game, osu?

M: Yeah it's like guitar hero except you pick the songs.

A: Wow sounds cool. How do I say it?

M: Oh-Sue.

Osu by Oh-Sue September 6, 2014

Osu 

(usually pronounced: oos )

A term used in karate or mixed martial arts schools meaning yes, hello, goodbye, and I understand. A general affirmative.

Teacher: Is everybody ready?
Students: Osu!
Teacher: Begin!

Osu by Guildenstern14 November 12, 2009

Osu 

A rhythm game by Dean Herbert where you click circles. It's also a game for problematic people and Anime Weaboos

Osu has not only wasted my brain cells, but it also caused me to have an addiction to anime and no friends. I can no longer call myself a normie.

Osu by WebooTrash April 6, 2019

osu 

Ohio State University

The home of the 2002 Ohio State National Champions.

osu by James Carpenter March 19, 2003

osu 

A Japanese Word meant to show respect. It's used for evens like Karate before the fight.

"OSU" pronounced like "os".

Osu - Let the fight begin

osu by James Laserbeem September 18, 2005

osu 

1) Oklahoma State University, located in Stillwater, Oklahoma with branches in Oklahoma City, Tulsa, and Okmulgee. Its official colors are orange and black, as opposed to colors picked by OU matching the blood on their white away-game uniforms. OU fans would resent this.
2) School that jealous OU people and OU fans hate for its superior academics and 43 national championships.

I went to OU instead of OSU because it was cheaper, there is no other logical reason.

I wish I had went to OSU because the dorms at OU are shit.

osu by Ross Moffett November 17, 2003

osu 

Oklahoma State University

OSU is a tight univeristy!

osu by Dizeb November 1, 2003