When a girl has herpes and makes a guy eat skittles out of her vag. He then eats a herpes cluster along with the skittle not realizing it. The girl's herpes is so bad it's in skittle sized clumps.
by Mustache McGee January 4, 2012

by Thomas Indy February 26, 2011

by Old Skool B-Boy May 18, 2004

is when u put skittles in water and then when they've lost all they're color, you skit all over tham and give them to someone u hate
by bob johnson May 13, 2005

by p00per September 8, 2010

The challenge of putting an entire bag of Skittles candies in one's mouth at once and eating them. Many videos of this can be seen on YouTube.
Mark: "Dude, you have to watch this. Steve's doing the Skittles Challenge!"
Tony: "No way, that sucks!"
Tony: "No way, that sucks!"
by crzypenguin October 13, 2010

Dude 1: "Dude that chick is smoken I'd eat that hot piece of pussy."
Dude 2: "Yea but I think she is on her period."
Dude 1: "Oh, F-that I'm not in the mood for any Vaginal Skittles."
Dude 2: "Yea but I think she is on her period."
Dude 1: "Oh, F-that I'm not in the mood for any Vaginal Skittles."
by TonguePuncher69 September 7, 2012
