A cup of what's up

promethazine mixed with sprite.

I had a long day at work, I can really use a cup of what's up to relax me.

by TheRig December 4, 2012

Knows what's up

If one knows what's up - they got it, have it figured out, the one you can trust in the specific situation they're the one to follow.

*someone talking about politics and solidarity on the telly* yeah, he knows what's up!

by Lowyflowy January 22, 2024

what up boyzzzz

WHAT????? U DONT KNOW WHAT THAT MEANS???? WOWWWW

AYYYYY WHAT UP BOYZZZZ!

by Whattupmynamebob March 4, 2021

Say what up to John

The act of taking a huge dab to become really high

Hey man, what do you say we go say what up to John after church?

by Dr. Anita Cain N’Degochello September 21, 2018