what's up with that

A phrase used after hyping someone up.

You been on your fitness lately. What's up with that?

by BEYONDaverageguy March 2, 2021

be like whats up

When whatever is being referred to is doing something it is not supposed to be doing or taking a form it is not usually in. Mostley used in dark humor.

(a chicken is found frozen and dead)
"chicken be like whats up"

by Bjapayot3 March 9, 2019

What’s up brother

A common saying/ greeting in the madden gaming community. Popularized by a streamer named Sketch. It is customary to raise you index finger while using this saying/ greeting.

Person 1: hey

Person 2: what’s up brother.

by PEEPEEHands04 May 6, 2024

whats up brothers

a way to greet someone in a funny or goofy way

whats up brothers

by imaslaywoman;) May 2, 2024

Say what up to John

The act of taking a huge dab to become really high

Hey man, what do you say we go say what up to John after church?

by Dr. Anita Cain N’Degochello September 21, 2018

what up boyzzzz

WHAT????? U DONT KNOW WHAT THAT MEANS???? WOWWWW

AYYYYY WHAT UP BOYZZZZ!

by Whattupmynamebob March 4, 2021

A cup of what's up

promethazine mixed with sprite.

I had a long day at work, I can really use a cup of what's up to relax me.

by TheRig December 4, 2012