When a photo has been digitally edited using 'Adobe Photoshop'. Typically not used for something made in the program, mainly for things that have existed prior and have only been changed in Photoshop.
Used sometimes as a stand in for 'edited', when the editing software used is unknown.
- Look, Obama is giving himself a medal!
- What the hell, that must be photoshopped.
- Of course it is you dumbass.