ultra down syndrome deluxe 

When someone has 92 chromosomes.

Jeff:Takes ur shield potion in fortnite
You:Whats it like living with ultra down syndrome deluxe?
Jeff:It's alright, I get a lot of free stuff

ultra down syndrome deluxe by Bucket0011 May 16, 2018

Metastatic Down Syndrome

When someone is so stupid that a simple retard won’t do

Durning an operation. The attending surgeons asks the resident to pull on something so he can see. “Hey pull on that like you mean it”. The resident then pulls too hard and causes audible bleeding! Surgeon says “what is wrong with you? Do you have metastatic Down syndrome?”

Metastatic Down Syndrome by Silver dollar tranny October 28, 2020

Double Down Syndrome 

A temporary loss of judgment and higher reasoning capability that one may experience immediately after consumption of KFC's double-down sandwich. Initial symptoms may include confusion, euphoria, and slurred speech. These are soon followed by loss of physical coordination and language ability (several patients have been observed to repeatedly utter variations of the phrase "hurr herp derp"). Patients may then enter a trance-like state for prolonged, variable amounts of time. A full recovery is typical within a few hours to a few days, although in some cases lasting brain damage has been reported.

In the hospital, it was discovered that what psychiatrists initially believed to be severe mental retardation was nothing more than a case of Double Down Syndrome after a late lunch.

Double Down Syndrome by theloniius April 12, 2010

Down Syndrome 

A condition affecting a person on the basic genetic level in which one chromosome splits in three instead of two and causes heart defects, thyroid conditions, shorter extremities and slower brain development. Although, their brains are slower to develop, you won't find any of them judging so harshly that they will be sending ignorant definitions out for everyone to see. They will also never judge you for having no genetic reason to be as stupid as you so obviously represent yourself to be, as referenced by your definitions.

My niece has Down Syndrome and she is one of the joys of my life. She is not ugly in body nor in spirit. In fact, she loves unconditionally, so unlike those of us who take kindness for granted so much that we forget how to show it.

Down Syndrome by fed_up_with_ignorant_people August 15, 2005

Down Syndrome Strikeout

when two homosexual boys with down syndrome sit on a couch by a warm cozy fire and take turns giving each other oral sex then all of a sudden one of them unexpectedly shoves the other boys entire ball sack in his mouth and gnaws the stretched skin off and swallows it whole then rips off his own testicles and wedges them inside of his asshole then takes his hand and slaps himself across the face then yells at the other boy in laughter and excitement"STRIKE THREE I'M OUT" then jumps into the fireplace. The other boy crys in agony because he knows he was defeated by a true champion.

Sebastian- I wonder what people with Down Syndrome do with there free time.

Derrik- They play Down Syndrome Strikeout

Sebastian- Whats that like retard baseball?

Derrik- Lets just say the two are quite similar.

Down Syndrome Strikeout by sacrifice snuggle August 10, 2010

Down Syndrome Anal Fun 

When two down syndromes experience anal sex for the first time.

Retard #1: Nar-Nar my penis

Retard #2: Hardy har har

This is what we call Down Syndrome Anal Fun

Down Syndrome Anal Fun by Bum Killas 101 April 10, 2009

Berry Down Syndrome 

The irrational belief by employers and supervisors that making use of a BlackBerry phone during the business day will result in a lack of productivity. Micro managers are usually afflicted by this disorder.

Susie: I'm off. I'm going to call my friend for a ride home.
Jojo: Down. Susie, down. Down. Put it down.
Susie: What the hell are you talking about?
Jojo: Down, berry down. Put it down. Down, put the berry down. Down, put it down. Down. Down.
Susie: You have Berry Down Syndrome, get help!

Berry Down Syndrome by Jocko Tam July 18, 2009