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Cock block

When a guy moves in on a girl that another man has began courting. Usually at a party/club/bar while the other man goes for a drink or to the bathroom but can also apply to any situation where a man has expressed interest in a girl and another man moves in without regard/respect. It is a sign of grievious disrespect and may result in shunning from the male group or a serious beating/pounding/rolling or other retribution. (also Cock blocker and cock blocking)
"I was talking to this girl and my buddy sat down on the other side of her and kept butting into our conversation trying to flirt with her, I'm gonna beat that cock blocker down!"
Cock block by Rob Batavia February 27, 2003
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Keele Cock Block 

Student accomodation in keele university. Situated in the Hawthorns. Called Cock Block because it is single sex. Well known for having the most fun of all the student in the entire world.
Cockblocker: I'm heading back to the Keele cock block, ya cumming hoe?
Girl: Yeh Keele Cock Block is the best, i'll let u shag me if you take me there.
Keele Cock Block by Jack Shaw December 21, 2007

inadvertent cock-block 

when your roommate cock-blocks you inadvertently, just because he/she lives there and wants to go to sleep, making it not really his/her fault, but frustrating all the same. This becomes even more frustrating when your partner has roommates as well, leaving you completely dry.
Last night I got hit by an inadvertent cock-block. Talk about frustrating.

Penta Kill Cock Block 

When you get a Quadra kill on League of Legends but someone on your team steals the last kill.
Ashe : Kill
Ashe : Double Kill
Ashe : Triple Kill
Ashe : Quadra Kill
Sona : Kill ( Troll )

Ashe : AKJSDHAISBDASDAS WHHYYYY
Ashe : You penta kill cock block'd me

Cock block

An act of obstructing one person's advances towards another or preventing a person from action, especially sex.
BABY MAMA: I'm talking to this guy now name Terrence. He's a nice and comical guy.

BABY DADDY: You gonna have to cut that man off, I don't care if he's nice or not, he better not be in the picture.

BABY MAMA: Oh, now you wanna cockblock for the simple fact that I moved on without your sorry ass.

cock block and roll 

Its when you're with some friends at a party or some sort of get together and one of your friends is flirting or gettin with someone and you need to leave.
Lets cock block and roll this mother f*cker

cock block

(n.) one who prevents another from getting "play", "poontang", etc.
(v.) any action that impedes or stalls another's "game", "mack", or "pimp manuver"
(n.) I was dancing with this girl, when this cock-block stepped in between us and started grinding with her.
(v.) I had finally convinced Susan to go to my friend's keg party with me, when my Dad cock-blocked me by taking away my car keys.
cock block by MCKREWGA September 13, 2003