TGISC 

Anagram which stands for "Thank God It's Stephen Colbert", visible in the opening sequence of Colbert's show, The Colbert Report.

It's 11:30 on a Wednesday, TGISC.

TGISC by sixeyes May 22, 2012

TGISC 

Thank god it's Stephen Colbert. Used when talking about the best comedian of these times.

Guy: "I hate life. My girlfriend of 10 years just broke up with me, I lost my lottery money in Vegas, and a I woke up to 6 cats mauling my face. There's no way I could got cheered up."

His only friend left: "Oh the TV's on. Let's turn to Comedy Central."

Guy: TGISC!!!! There is a god, and he's in my TV!!

TGISC by The blind man driving. August 5, 2012