by DMasSC November 23, 2007

To smoke weed until you're retarded, as Down's Syndrome is cause by the presence of an extra chromosome.
Chich : We finished a quarter ounce between us last night, man. I think I'm still kinda faced.
Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.
Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.
by Parhelion February 22, 2009

by hteb78 April 29, 2013

It basically means to leave someone alone when they do something wrong. Also used as "spare me some". Example: at work, you may have done something wrong. Your boss is screaming at you, and you use this phrase.
Boss: "You idiot! You made this company lose one billion dollars!" You: "Calm down boss. I'll pay it back. Spare me some shit."
by Singled_Out_alone May 11, 2014

Normally used when a black, or African-American individual likes white, or caucasian individuals. This is where the idea that white people are "snow" ; so when someone says "you like to ski" it is referring to liking white people in a romantic way.
Cheyenne: Girl that black guy is sooo fine!
Janice: Girl, dont even bother. He likes to ski on his spare time.
Janice: Girl, dont even bother. He likes to ski on his spare time.
by cheerlife2 July 11, 2011

When the lampshades and gas chambers aren't real but you still get to round up to six million, you might be picking up the Jewish spare.
by Indigo Mandingo January 11, 2019

by Swiftyboilad12 November 4, 2018
