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skittles 

anotha word 2 say drivin sum1 crazy or "up the wall"
Yo dis dude is drivin me skittles
skittles by $iKwItIt June 4, 2005

Skittles 

Street name for Salvia.

Often used in front of people who don't agree with taking salvia.
Mainly parents and teachers.
Person 1: so are we doing skittles next week?
Person 2: yeah, but why you calling it skittles.
Person 1: i thought the teacher was listening.
Skittles by melikeganja January 30, 2010

Skittles 

Another word for candy-coated Meth.
"Hey man, can I hit you up for some skittles?"
Skittles by NocturnalCutie May 2, 2010

skittles 

a random uniform / un-uniform assortment of pharmaceutical / pill(s) that make people giggle & smile more like a young person eating the S painted jewels
Yo this exam safety officer talked about he liked referring to those safe & effective smilers ... like I said them skittles , old tripped epic hard cant take a kleenex inside smiler

Our super seniors & skinny hoes love them skittles
skittles by safetyadvisor29 September 25, 2011

Skittles 

Hard Nipples on the female titties - the big things or boobs.
Come and suck on my tasty ass skittles.

skittles 

A girl who has been with every racial color of the rainbow.
Where is that white girl Skittles at?
skittles by belvedere January 9, 2015