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Guitar Hero Itch

The annoying and inevitable sensation of an itch at any place on the body that occurs while playing Guitar Hero.
Mandy: "My arm itches, but I can't scratch it because I have to keep playing!"
Claire: "I know how you feel; my nose has been itchy for the last 5 minutes, but there hasn't been a break in my notes. Damn you Guitar Hero itch!"
Guitar Hero Itch by Klair February 18, 2008
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Guitar Hero Hand Syndrome 

Guitar Hero hand syndrome is what happens when you play guitar hero for a very long time (5+ years) and whenever a guitar solo or any music that you can follow along to you start playing air guitar and it really does not make you look cool it makes you look more like a poser
Person 1: Man i think i been playing Guitar Hero for to long i think i have Guitar Hero Hand Syndrome *starts playing air guitar*

Person 2: Dude stop playing that silly game and start playing real guitar

Guitar Hero 4 

Neversoft's answer/copy of Harmonix's Rock Band.
Bob: Hey you know Guitar Hero 4? It's going to have drums and singing!
Bill: Oh, you mean just like Rock Band?
Guitar Hero 4 by hhcash June 15, 2008

Guitar Hero ramble

The act of or talking in complete shit, while playing the game Guitar Hero.
While playing the new Guitar Hero 3 game, my friend, Josh Duncan, started shouting Guitar Hero ramble. Which in return made me mad, because i was asking him about Bebo, and the genius that he is answered, "Chicken."
Guitar Hero ramble by Josh Beck December 16, 2007

Guitar Hero Bends 

The sensation that the room is spinning or melting after playing long sessions of Guitar Hero. Also a similar sensation to tripping balls
"Man this room got all messed up after i stopped playing" "Nah you just got the Guitar Hero Bends"
Guitar Hero Bends by Poptart419 January 3, 2010

guitar hero syndrome 

when some one has been playing guitar hero for so long on expert they think the are a real guitar hero but really if you gave them a real guitar it would sound like a cat drowning whan they played
guy1: hey i just did 'dragonforce' 'throught the fire and the flames' on guitar hero 3 on expert 100%

guy2: wow really have a go on my les paul special

guy1: ok sweet *picks up guitar* *&$$&%#^%^#^&^(*$%$#@#$7 *plays horibble*

guy 2: put my guitar down the the hell outta my house and never speak to me again, buy a real guitar and get over your guitar hero syndrome u noob ass-raper
guitar hero syndrome by btf'07' January 8, 2008

Guitar Hero III

A) Third numbered installment in the Guitar Hero franchise (fourth including Guitar Hero Encore: Rocks the 80's). Unlike the previous games, which were developed by Harmonix, Guitar Hero III (henceforth GH3) was developed mainly by Activision in an attempt to ride on the success of the previous Guitar Hero games. GH3 features a soundtrack full of artists befitting of it's subtitle "Legends of Rock." Artists like "Die Toten Hosen," "Héroes del Silencio," and "Eric Johnson." GH3 also attempts to pull the player more into the story of the game through animated cutscenes. It also adds battles with famous guitarists like "Tom Morello" and "Slash," these battles are essetially glorified versus mode except that the AI controlled character never makes mistakes unless you use a power up. It should also be mentioned that the final battle against Lou (the devil) is basically impossible even on easier difficulties without play it multiple times and hoping that Lou gets the less deadly powerups. It also adds a new Co-op career mode with songs that cannot be unlocked in any other mode, this means that if you own the PS3 or Wii version of the game you must buy another copy of the game to get another controller so you can play through co-op career in order to play these songs. For those that played the Playstation 2 version of GH2, the third installment adds downloadable content (DLC) in the form of additional songs, most of which are piss-poor songs/bands which no one wants to play and all of which are horribly overpriced (about $2.50 per song or $6.50 for pack of three songs (song packs and individual songs are separate and a song that is available in a song pack is not available individually and vise versa)). DLC is only available on the XBox 360 and Playstation 3 versions of the game. Completely new to the franchise is online play, now you can face off against others online (provided you are playing the XBox 360 version as the PS3 and Wii online modes rarely work).

B) A rhythm game for people with no friends (compare to Rock Band: a rhythm game for people with friends)
A: Hey wanna come over and play Guitar Hero III with me?
B: Nah, me and some guys are gonna go play Rock Band. We're finally gonna hook it up to the internet to get some of the 60+ songs that have been released for DLC.
Guitar Hero III by andyscout March 3, 2008