stands for "It's Senior Year". ISY can be used interchangeably with "YOLO"; it is used to justify otherwise questionable behavior during the final year of high school or college.
by killemandgrillem69 February 21, 2014

To go crazy and or/do something fucked up while disregarding any sort of morality for a short stint of time.
''You should have been at that brothel last night dude. Dave went isis on three hookers..'' ''What did he do?!'' ''He started shouting Allahu Akbar and then dived through a window with two hookers under his arms''
by finnn June 6, 2015

by Dadbagh October 11, 2017

OMG hes muslim so he must be a part of ISIS even though Islam means peace but i'm to arrogant to realise that.
by Al Jordeno March 14, 2016

by THE OG OG MUDBONE March 17, 2016
