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"Fuck 12" means fuck the police (12 narcotics officers) the saying "Fuck 12" is mostly used in Atlanta Georgia and Oakland Ca.
MIGOS -FUCK 12 (12 kicking in tha front door)
fuck 12 by Trap boy 25 March 16, 2014
Yo fuck 12 dude
fuck 12 by Egdelord Mommy September 30, 2021
Fuck the police.

It is said to originate as the result of the TV show Adam-12, to be in reference to a narcotics unit, or a radio code used by police themselves.

An organizer in Chicago told me that it's because when you read police reports of when they murder someone, it's narrated from the point of view of the cops (at 12 o'clock).
La policía, la migra, la misma porquería. Fuck 12.
Fuck 12 by NoCopAcademy April 17, 2019
Man I got pulled over for being black on a Friday night. Fuck 12!
Fuck 12 by Fk12 August 31, 2018
Daquan - Dude don't spray paint the bridge! You're gonna get arrested again!
Mikel- Man, Fuck 12.
Fuck 12 by blankets4life August 8, 2017
i walked by the police station and said fuck 12
fuck 12 by yuh boii bailey April 21, 2017