Fuck 12 basically means fuck the police, but more specifically it’s means fuck the police drug unit.
Dashawn: “man close the window, the 12 might come!”
Daquan: *hits blunt* “man fuck 12!”
by Jellyfiish July 20, 2018
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Fuck the police.

It is said to originate as the result of the TV show Adam-12, to be in reference to a narcotics unit, or a radio code used by police themselves.

An organizer in Chicago told me that it's because when you read police reports of when they murder someone, it's narrated from the point of view of the cops (at 12 o'clock).
La policía, la migra, la misma porquería. Fuck 12.
by NoCopAcademy April 17, 2019
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Daquan - Dude don't spray paint the bridge! You're gonna get arrested again!
Mikel- Man, Fuck 12.
by blankets4life August 8, 2017
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The word is used to mean fuck the police.

You probably saw it on tv, US protestors spray on police cars and walls of public buildings and white house during the protests of the murder of George Floyd in 2020.
The number 12 reps the narcotic police and can also be used to mean 911. 9 is one and 1's are two.
Q. Why are you spraying the popo's car?

A. Man Fuck 12
by @Lwixe June 3, 2020
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“Fuck 12 man, they’re gonna get us
by XxxmoonlightxxX November 21, 2018
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