mother heffer 

1. Fat Bitch
2. A woman whos eating has no limitations.

Tommy: Mommy that lady's ass keeps growing!
Mom: Leave the mother heffer alone shes too ugly to have sex!

mother heffer by ThePatriot March 29, 2004

mother heifer 

circa 2005
country of origin: Katie Abbott

Mormonized version of the colloquial profane statement: "Mother F'er" or "Mother Fucker".
Logically followed more archaic statement "Mother of Cheese" which is, in fact, a cow, or a "mother of a heifer".

random guy on college campus: "Dude, did you just see that hot girl go by on her Razor scooter? She totally just biffed it."
random hot girl on scooter: "MOTHER HEIFER!"

mother heifer by Samantha Winter March 29, 2005

mothereffer 

Mothereffer is far less-profane an alternative to motherfucker and more socially acceptable in mixed company.

That mothereffer Frank is the captain of the hockey team and the football team and gets all the fine looking girls!

mothereffer by brandon667 January 14, 2010