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cheese sliding off the crackers 

To go totally insane, in the same vein as losing one's marbles.
Phil threw another tantrum over a missing sock. I think he's got his cheese sliding off the crackers.

Sliding the Cheese 

When a man performs cunnilingus on a yeast infected vagina, collects all the "yeasties" on his tongue and French kisses the woman.
This girl had a yeast infection and asked me if I was down for sliding the cheese with her and some close friends.