Colon Jello Share definition Flag A thick substance that oozes from the rectum. Usually after the consumption and attempted digestion of Taco Bell. "Cindy ate some of my colon jello with whipped cream." Colon Jello by Logan Heckyes January 28, 2013 0 0 Get merch Get the Colon Jello mug. Buy Now — $32.95 See more merch