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1. past part. of spiff (to groom or make attractive) usu. spiffed up; also, well-dressed

2. Intoxicated esp. to a level of severely impaired motor and cognative function, usu. from ingestion of alcohol or alcohol in conjunction with other illicit/illegal drugs
1. "My dentist really spiffed up his waiting room over the summer!" or "My roommate spiffed up for his date tonight."

2. "After four shots and six beers, I was so spiffed I couldn't stand up." or "I was a little drunk when we got to her place, but after we smoked a couple bowls I was totally spiffed!"
spiffed by Johann7 December 18, 2006
Related Words
Staffed is literally translated as confused. However, its popularity as a word has recently declined. Immediately after creation by the G.O.A.T, it was a very popular word. Everyone was staffed. But times have changed. The word staffed is now almost exclusively used in the Staffordshire region. The young ones prediction wasn't correct- "its not gonna be as big as o my, but its definetly gonna be big." No halz.
O dear halz we are staffed!
staffed by please calm October 16, 2006
The goings on now- where in retrospect would be considered a snafu
Dude! Watch out or we'll all be totally snaffed!
snaffed by Jeff Fire December 13, 2008
To be swagged, to the level where the word swag is no long swag.
Person 1:Do you see that girl karlee?
Person 2:Yeah man, she has swag.
Person 1:lol, yeah. Sh.. Whoa do you see Thomas?
Person 2:Dang that boy is lookin spiffed today.
Spiffed by Kawika Swag. May 28, 2011

Spuffed it 

Messed up
Messed it up
Fucked up
Fucked it
How did it go last night? “I don’t know man I think I spuffed it with her badly!”
Spuffed it by TheOnlyTurnip August 19, 2019

Spiffed up 

When a man is dressed up in a full suit and tie, again for a reason or on a whim to look hot.
Matt found out the girl he likes is interested in classier men, so he got spiffed up every day to impress her. Even though it was uncomfortable for him, she found his level of spiff pretty hot.
Spiffed up by Knotted up May 18, 2020