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Mass Effect 2 

Mass Effect 2 by AxiomD February 6, 2010

Post Mass Effect Depression 

Sometimes associated with the "Mass Effect effect", this feeling comes from the completion of the Mass Effect game series. Common causes include getting immersed so much in the game that after completion, you feel lost and/or empty, or realizing that the Mass Effect universe is so amazing compared to our own and you're pushed down by the fact that you'll never be a part of it.

To be less extreme, people may feel empty because they realize that no other game will ever be as immersive as the Mass Effect series, thus ending their gaming career forever.
A common outcome of Post Mass Effect Depression:

"No girl like Tali'Zorah nar Rayya exists in our world..."

*gunshot*

Mass effected 

Being addicted to the video game series Mass effect by Bioware.

By reading the books, owning a item of Mass effect, or playing the game more than 6 times.
Jake keeps saying that, "Mass effect will suck you in like a black hole!"

He is Mass effected.
Mass effected by BigJK June 8, 2011

Masseffecturbate

To occupy ones time by playing Mass Effect or Mass Effect 2 (Mass Effect 3 will be included when it comes out), instead of hanging out with friends or doing more important things.
Yo Eliot, why didn't you wait for us to pick you up from the movies? What, you couldn't wait to get home to Masseffecturbate.
Masseffecturbate by Gnezz10 February 25, 2010