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In Space With Markiplier 

Free!!
(And coming out on April 4 2022)
(On YouTube)
(For free)
Hey, have you heard of 'In Space With Markiplier,?
No I haven't but I probably couldn't afford it anyways!
Haha you fool, it's free!

In space, no one can hear you scream. 

This is the tagline for the film Alien, which was directed by Ridley Scott, not James Cameron, as currently stated on this site. Cameron directed the sequel, Aliens.
"In space, no one can hear you scream." is on e of the most quoted and parodied timelines in film history. It would have been more accurate if applied to Cuaron's Gravity, in which the silence of space plays a role in the narrative.

time and relative dimensions in space 

T.A.R.D.I.S. It refers to the Gallifreyan time and space travel capsule which is dimensionally transcendental (bigger on the inside). The most common example is the one used by the Gallifreyan Time Lord known as "The Doctor", that is permanently disguised as a 1960s police telephone box.
Susan: I made up the name TARDIS from the initials - Time And Relative Dimensions In Space.

Lost in space 

Synonym for someone who is either high or suffering from a delusion. From the 1960s television series "Lost in Space" where a group of travelers found themselves stranded on an alien world.
That guy is truly lost in space. He's out of it.

He Can Breathe In Space 

A phrase for anyone who seems able to do anything, or able to do something amazing and uber.

Comes from the comic Shortpacked!, in which it was used to describe Batman.
"Dude, did Iroh just firebend LIGHTNING??"
"He's the Dragon of the West! He can breathe in space!"

I'm in space 

when you are obsessed with something, and then FINALLY, after AGES of wanting to do it/ go there, you get to, and you are so excited that you go crazy
When Wheatly was portaled to the moon in Portal 2, the first corrupt core attached to him, obsessed with space, repeatedly uttered the phrase "I'm in space"