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to leave or depart hastily (from Spanish, Vamos meaning let us depart)
I've gotta vamoose or I'll be late.
Related Words
Scram, take off, go away, gtfo.

Comes from the Spanish vamos - the word transitioned into American English as a result of contact with the Spanish colonies in Mexico.
Trust me holmes, you don't want to start shit with me. Vamos, esse.
vamoose by Tronno August 27, 2005
Jay-z's Song "poof, vamoose son of a bi***"
vamoose by Ariana March 29, 2004
Move now, get out of here, move your bottom please.
Gardener to flock of distructive birds: vamoose you darn birds!!
vamoose by crayola March 30, 2004
You - you're bugging me. Vamoose.
vamoose by DHG March 30, 2004
You'd better vamoose before my girlfriend catches us.
vamoose by LB March 31, 2004