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1. A relatively permanent change in hereditary material involving either a physical change in chromosome relations or a biochemical change in the codons that make up genes; also : the process of producing a mutation

2. An individual strain or trait resulting from mutation

3. Very rarely used term by young gay people themselves who feel unattached with the mainstream because of either shyness, bullying by others and or being a homosexual.

4. A class of Superhuman Beings (Homo Superior) in the Marvel Comics Universe who are born with latent abilities far surpassing that of regular Humans (Homo Sapien).
1) Virtually every living thing is a mutation.

2) See example 1.

3) " I feel I am a mutant, being a gay man I know what being a mutant must feel like." - Sir Ian McKellen

4) The X-Men are a group of mutants who try their best to protect a world that hates and fears them.
Mutant by Cryo-Morph X September 21, 2003
The Attorney in "Fear and Loathing in Las Vegas". Oscar Zeta Acosta. Dr. Gonzo, partner of Raoul Duke.
“There he goes. One of God's own prototypes. Some kind of high powered mutant never even considered for mass production. Too weird to live, and too rare to die.” - Hunter S. Thompson
Mutant by Nemo1080 September 16, 2009
Derogatory term/ slang used in reference to a person from the Gary-Hammond metropolitan area of Northwest Indiana. Origin of the word is either a reference to the high amounts of pollution or unique patchwork culture that "Mutates" its inhabitants. Although the term's creation was intended to insult it is now used as a term of endearment among residents.
Yea, he works in Chicago, but he's a mutant
Mutant by Histprof December 14, 2010
Sick is a word used by most chavs, meaning "very good".

Non-chavs are adopting the word "mutant" as their equivalent of "sick"
"Wow Jamie, your new hoodie is Mutant!"

"The party last saturday was fucking mutant!"
Mutant by Jamie_Marlow_1991 January 18, 2009
See: Pete Winkelman
See: Lee Scriven
See: Raj Parker
See: Steve Stride
those nasty mutants (for explanation see Franchise FC, AFC Wimbledon or Pete Winkelman
mutant by AFCW April 24, 2004
An opiate-based pain medication abuser or junkie who is noticeably high in public, an opioid addict who doesn't care how they are perceived in public, a heroin or opioid abuser who is seen attempting to go about their day in public but is so high that everyone around them knows they are very high. Signs to look for-dilated pupils, slow movements, disheveled hair, dirty clothing, speech is incoherent, and the person may slobber or drool. DO NOT CONFUSE WITH A HOMELESS PERSON. A mutant IS NOT a recreational drug abuser/social drug user. A mutant may appear like a zombie stumbling about until they finally pass out for one of their frequent naps.
"Look at that line of mutants outside the pain clinic. Man every one of them is shaking from withdrawl and they look like they haven't showered in a week".
mutant by OXYCop August 23, 2010