Zyst 

A cyst that also has many of the same characteristics of a zit. Often seen as a large raised redish area on the skin.

Elliot wants to pop the zyst on his neck, but he really should see a doctor instead.

Zyst by DoWhat? August 25, 2009

Zyst 

The crappy new name of RSC king/queen Mystress.

"Mystress' new name sucks...who would want the name Zyst?"

Zyst by ~ December 16, 2004

zyst 

n. A giant, angry, throbing, pus-filled bump; part zit, part cyst

My blind date was a nice enough guy but, I was fearful that the zyst on his face could erupt at any moment!

zyst by tboone March 13, 2010

zysterphysting 

to peel off dead skin or scabs while smashing

yo me n emily where zysterphysting so hard last night

zysterphysting by zysterphyster April 29, 2023