Machoyz Share definition Flag Machoyz is a term used to define something very cool. Pronounced MUH-CHOIZE. Dude, That movie last night was so machoyz!I had sex with Karen last night, and her vagina was not machoyz! Machoyz by Sleft June 17, 2009 0 0 Get merch Get the Machoyz mug. Buy Now — $32.95 See more merch