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the zactly disease 

a condition in which your face looks 'zactly like yo' ass.
Your mom's so ugly that just one look at her gave me the zactly disease.

zackley's disease 

Pungent feet stench, that can drive away normal humans on a range of 15 meters, and allure carcass-eating beasts like vultures and hyeenas.

Firstly acknowledged in Pantera's video "Three - Watch it Go!", by Dimebag Darrel, Phd.
John Doe: "Whatta hell is that stench?"
Jane Doe: "It's your mother. She has zackley's disease. Die."