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Gonnosyphiherpeclap 

The worst kind of sexually-transmitted disease you can possibly get.

It's a mixture of Gonorrhea, Syphilis, Herpes, and the Clap.

Pronounced: Gone-a-sif-a-herp-a-clap

It is also customary to clap once when somebody says this
Man 1: Dude, that girl is a total slut...she freaking gave me Gonnosyphiherpeclap.

Man 2: *Claps hands once*

Man 1: What the fuck was that for?

Gonosyphiherpaclap 

A mixture of several STDs several of which includes Gonorrhea, Syphilis, and Herpes.
Tim: Man, I think Brittney gave me that gonosyphiherpaclaps.
Jim: You mean gonosyphiherpaclap?
Tim: Nope, the whole time she was clappin so loud I could hardly hear.
Gonosyphiherpaclap by xJoshx February 6, 2008