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Properly written: ¡Ay, güey!

It is a very informal Mexican exclamation, similar to "OH, SHIT!" without the intense level of vulgarity.

It comes from: Ay! - literal translation of exclamation in Spanish of "OH!/ Ouch!"
Güey! - refers to "dude / chav" hence why it is informal.
Ay wey, tu jefa esta bien buena. - "Oh, dang! Your mom is so hot."

Ay wey! Casi me caigo! - "Oh, shit! I almost fell down!"

¡Ay, wey! Ya no tengo dinero. - "Oh dang. I don't have anymore money!"

Ay, wey. Se me pasó el camión. - "Oh, shit. I missed the bus."

— ¡Ay, güey! — Exclamó Eratóstenes. - "Oh fuck!" Exclaimed Eratosthenes.

**Either spelling is equivalent to mean the same thing, except "ay wey" is more prevalent in informal writing or among anyone basically (refer back to the fact of being an informal expression). "¡Ay, güey!" is more prevalent in literature but is not exclusive.
Ay wey by tehlostghoat May 26, 2020
Related Words
ay wey!! ay ay-yo ay bay bay ay ay ay ay m ay mane ay mo ay ay ay dios mio
Upon hearing that all Northern Mexicans whose family name ends in a Z are descended from Jews who fled the Inquisition, and that is why they eat unleavened flour tortillas and why abuela sweeps from the corners of the room to the center every Friday, Jesus exclaimed "ay wey!"
ay wey by skintigh September 2, 2010