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getting after it 

When a group decides they are going out HARD for a night of drinking they are said to be, "getting after it"
Dude, I've made an executive decision. It's been a long week and we ARE getting after it tonight.
getting after it by Andrew1122 February 26, 2008

getting after it 

taking it to the max, abusing substances to the point of annihilation, 6/24/10
Wow, we were definitly getting after it last night. I woke up in a field wearing only a burger king crown.
getting after it by Big B 143 June 28, 2010

getting after it 

To drink alcohol and get shitfaced.
Rick: Yo what are you doing tonight?
Bmurph: We're going to the bar and getting after it.
getting after it by Slick Ricky September 18, 2008