1 definition by eviljungleprincess

The female noun/verb combo of the very popular "cockblock" or "cock block". A muffcuff occurs when a female is twarted from her goals or desires by someone else. The person doing the thwarting (aka the muffcuffer) could be a person, place or thing, or even a vague, abstract concept.
omg that ho totally just muffcuffed me when she showed her slutty cleavage to the bartender.

Why you always gotta be muffcuffing me?

Oh, snap! That muffcuff was hella harsh.

I'd much rather be a muffcuffer than a muffcuffee.

(archaic) Alas, thy wench muffcuffed me. In the 'morrow, I shall tell her to "get thee to a nunnery".
by eviljungleprincess August 19, 2010
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