1 definition by TheBarsMyDestination
A reaction to taking a new drug or medication that is so abrupt and paradigm-breaking that one immediately realizes that life, and one's perception of it, has been fundamentally and irreversibly changed. Named so in analogy to a religious experience, and as a portmanteau of "pharmaceutical" and "Damascene conversion".
Yeah, I was in pretty bad shape when the EMTs pulled me out of the wreck, but then they put the morphine in the IV and... man, I had a pharmascene conversion.
by TheBarsMyDestination July 26, 2018