An important comment during conversation when it is more significant than previous statements and/or taking place immediately after being said, needing the utmost attention from the other person.
Scene: 1:03am on a Wednesday night
That Guy: "Yeah, you're so awesome
. Blah blah blah blah..."
That Girl: "Front note: I know I'm awesome
, but you have to quit talking to me. I have to go to bed."