3 definitions by SoyMilk181

A deadly contagious syndrome that can cause particles, situated in ones testicles, to expand over the span of around 16 weeks, and eventually explode the shit out of their ballsack.
“guys… GUYS… DAVE HAS BIG SYNDRO-”*death*

Nobody:
Doctor: “Sir, I’m afraid you have been diagnosed with… big syndrome. I can approximate about 12 more weeks left for you to live. I suggest you move to a far, deserted island before it’s too late.”

“Yo guys, I’m gay”
by SoyMilk181 March 7, 2023
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